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Cialis is readily absorbed from the bloodstream. It is about 16% bioavailable. Tadalafil is about 94% bound to plasma protein. Maximum plasma concentration of Tadalafil was achieved 2 hours post dose. The Cialis label states that It can be taken from 30 minutes to 12 hours prior to sexual activity. Efficacy of tadalafil may persist up to 24 hours post-dose.

Dose:

Cialis is available 10mg and 20mg tablets. The recommended dose is 10mg taken prior to anticipated sexual activity and without regard to food. In those patients in whom tadalafil 10mg does not produce an adequate effect, 20mg might be tried. It can be taken from 30 minutes to 12 hours prior to sexual activity. The efficacy of tadalafil may persist up to 24 hours post-dose.

The maximum recommended dose is one pill per day.

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