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Cialis is mostly metabolized in the liver by an enzyme known as CYP3A4 and to a lesser extent CYPC2. Tadalafil breakdown products are excreted in the feces (61%) and in the urine (36%). Cialis’ mean half life is 17.5 hours in healthy men.

If you are going to take any of the PDE5 inhibitors such as Cialis, it is very important that your doctor be aware if you have a liver condition (such as cirrhosis) or kidney condition ( such as if you are on dialysis) because you may need a special dosage adjustment.

Likewise, if you try to obtain Cialis on the internet, please make sure that the person authorizing your prescription knows the true status of your liver function and your kidney function.

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This entry was posted on Tuesday, November 6th, 2007 at 3:36 pm and is filed under General Information. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.