Archive for July, 2008

New Clinical Data Show Patients Receiving Cialis - tadalafil - Improved Intercourse Success at 24 and 36 Hours After Dosing

Sunday, July 27th, 2008

According to newly released clinical data on Cialis(TM), an investigational PDE5 inhibitor being developed by Lilly ICOS LLC for the treatment of erectile dysfunction (ED), men with ED reported a statistically significant improvement in successful intercourse attempts at 24 and 36 hours after taking the drug, compared to placebo.

These and other new findings - including a summary of cardiovascular safety data that showed no increased incidence of cardiovascular events during clinical studies - are being presented at the 97th Annual Meeting of the American Urological Association.

Cialis Period of Effectiveness - Key Study Findings:

In a Phase III clinical study designed to evaluate the efficacy of Cialis at specific time points after dosing, 1348 men with mild-to-severe ED were randomly assigned to receive Cialis 20 mg (n=175) or placebo (n=173) over approximately an eight-week period. Patients were instructed to attempt intercourse with their partners on four specific occasions: on two occasions at 24 hours after dosing and on two occasions at 36 hours after dosing. The primary endpoint was the percentage of successful sexual intercourse attempts.

Cialis Quick Facts

Sunday, July 13th, 2008
  • Cialis works quickly, most men report enhanced erections within twenty minutes of taking Cialis
  • Cialis has been called the “weekender” individuals can take the medication Friday afternoon and have enhanced erections for the entire weekend.
  • Cialis has now been approved in both the United States and Europe for the treatment of impotence

Cialis is unique from the other erection enhancement drugs, Viagra, Levitra, and Uprima, in that, Cialis will enhance erections for a long, long time following a single dose. Some ninety-five percent of the men during clinical trails stated that they had enhanced erection for 24 to 36 hours following a single dose of Cialis.

“Cialis has the potential to be a valuable new treatment option for men with ED and their partners,” said Dr. Harin Padma-Nathan, urologist and lead investigator of the study. “A therapy that allows a man with impotence to engage in intercourse within a 24-36 hour window permits the couple to regain spontaneity in their sexual relationship.”

Imagine, taking one Cialis pill on Friday afternoon and having an entire weekend of enhanced erections. No the impotence drug can compete with Cialis ability to enhance erections for such a long period.

FDA OKs Once-Daily Cialis

Sunday, July 6th, 2008

Men taking the erectile dysfunction drug Cialis may now take a low dose of the drug on a daily basis.

The FDA has approved once-daily use of Cialis in a dose of 5 milligrams or a new 2.5-milligram dose for the treatment of erectile dysfunction (ED).

Once-daily Cialis “may be most appropriate for men with ED who anticipate more frequent sexual activity (e.g. twice weekly),” states a news release from Eli Lilly and Company, which makes Cialis.

“For other men, Cialis taken as needed — the previously approved dosing regimen — may be most appropriate,” the drug company notes.

The FDA approved the once-daily Cialis dosing plan on based three studies in which 2.5-milligram or 5-milligram daily doses of Cialis trumped a placebo pill. In those studies, men took Cialis every day without regard to the timing of their sexual activity.

The FDA first approved Cialis in 2003 in doses of 5 milligrams, 10 milligrams, and 20 milligrams.