Archive for October, 2008

FDA Approves Cialis (tadalafil) for Once Daily Use for the Treatment of Erectile Dysfunction

Tuesday, October 28th, 2008

Eli Lilly and Company announced that the U.S. Food and Drug Administration (FDA) has approved Cialis® (tadalafil) for once daily use (2.5 mg and 5 mg), an oral medication taken once per day to treat erectile dysfunction (ED). When Cialis for once daily use is taken daily, men can attempt sexual activity at anytime between doses.

Currently available in parts of Europe, this low-dose daily treatment option of Cialis may be most appropriate for men with ED who anticipate more frequent sexual activity (e.g. twice weekly). For other men, Cialis taken as needed - the previously approved dosing regimen - may be most appropriate.

In clinical trials, when taken without restrictions on the timing of sexual activity, Cialis for once daily use improved erectile function over the course of therapy.

“ED can be a chronic condition like diabetes or high blood pressure,” said Ridwan Shabsigh, M.D., Director of the Division of Urology at Maimonides Medical Center in New York. “As a urologist, I know couples like to have choices and will appreciate the availability of Cialis for once daily use.”

Cialis for use as needed transformed the U.S. ED market when it was approved in 2003 as the first and only PDE5 inhibitor clinically proven to provide sustained efficacy for up to 36 hours. Cialis for once daily use provides a new option for men who may be looking for a dosing option that can be taken without regard to timing of sexual activity. In consultation with their physician, patients now have the freedom to choose the dosing regimen that is appropriate for them.

Additionally, Lilly’s wholesale pricing for Cialis for once daily use will be comparable to Cialis for use as needed such that patients who currently use two or more pills per week of Cialis for use as needed should not experience higher treatment costs with Cialis for once daily use.

The FDA’s approval of Cialis for once daily use was based upon the evaluation of the comprehensive data package for the daily dosing option. The data include results from three phase III randomized, double-blind, placebo- controlled studies. Men with ED who participated in these clinical studies and who took tadalafil 2.5 mg and 5 mg once daily without regard to their timing of sexual activity experienced improved erectile function compared with those taking placebo. Cialis 5 mg, 10 mg and 20 mg have been approved in the United States for as-needed treatment of ED since November 2003.

The most commonly reported adverse events were headache, indigestion, back pain, muscle aches, nasal congestion, flushing and pain in limb. Most adverse events reported with tadalafil were transient and generally mild or moderate.

How to Buy Cialis Online

Monday, October 20th, 2008

Step One: Do Research

Before purchasing Cialis online, you need to make sure that Cialis’s right for you. Visit Icos’s official Cialis site for detailed information on the drug, including possibly dangerous drug interactions. Bottom line, if you are taking any medications or have any health problems, we recommend you consult with your family doctor or pharmacist before buying Cialis online.

Step Two: Choose a Reputable Online Pharmacy

Obviously, you need to pick a reputable online pharmacy to purchase your Cialis.

Step Three: Fill Out the Health Questionnaire

If you don’t already have a Cialis prescription, the online pharmacy can provide one for you. They do this by having you fill out a detailed medical questionnaire to guarantee it’s safe for you to take Cialis. It’s important to fill out this information fully and accurately. Usually there is a charge for this service, but only if you are approved for the prescription. If you aren’t, there’s no charge. So be honest, your health depends on it.

Step Four: Choose Your Dosage

Cialis comes in 2 dosages: 10 mg or 20 mg doses. The most cost-effective way to purchase Cialis is to buy the 20 mg pills and cut them either in half or in fourths. You can purchase pill cutters at your local drug store for this purpose or just use a knife. 20 mg is a high dosage; you should start with a quarter pill (5 mg) and see how that works before using any more.

Step Five: Place Your Order

Once you’ve filled out the medical questionnaire and chosen your dosage, place your order. A doctor will review your order and if you get the prescription, your Cialis will arrive in a few days. For U.S. residents it may take a little longer depending on what type of shipment you choose. It’s a simple process and worth doing if you want to experience Cialis for yourself.

Facts about Cialis and Erectile Dysfunction

Monday, October 6th, 2008

Cialis is one of the popular medications in treating erectile dysfunction or impotence. Cialis works by relaxing your muscles and increasing the blood flow to certain areas of your body. It can also be used for other medicinal purposes as prescribed by your physician.

If you wish to take Cialis, make sure you are not using any kind of nitrate medications for heart problems and chest paints. These drugs include nitroglycerin, isosorbide mononitrate and nitrite. This is an important precaution because nitrate medications could cause a major decrease in your blood pressure, which could lead to fainting, heart attack, or stroke.

Cialis cannot be taken more than once each day. You should allow at least 24 hours between each doses. If you experience painful erection or an erection that lasted longer than four hours, seek immediate medical attention. Be aware that priapism (a condition wherein erection is prolonged) could damage your penis.

Any time during your Cialis medication and you experience dizziness, nausea, pain, numbness, hives, allergic reactions, difficulty breathing and tingling of your jaw, arms, neck or chest during sexual activity, immediately stop taking Cialis and seek for medical attention. These conditions are the severe side effects of Cialis.

Sudden vision loss is a rare side effect of Cialis medication. This is caused by the decrease of blood flow to the patient’s optic nerve. There is no medical evidence to prove that Cialis caused this kind of vision loss.

However, patients who have reported Cialis to cause vision loss are diagnosed with diabetes, high cholesterol, heart disorders, high blood pressure, existing eye problems or people with smoking habits and those above 50 years old. Regardless of Cialis’ relation to vision loss, it is recommended that you discontinue Cialis medication when you experience sudden loss of vision.

Serious side effects of Cialis include chest pains, nausea, sweating, irregular heartbeats, swelling of hands, feet or ankles, difficulty of breathing, lightheadedness, fainting, vision changes, painful penis erection or erections that last four hours and longer. When any of these side effects occur, stop using Cialis and immediately consult with your doctor.

Minor side effects of Cialis include redness of chest, face, or neck, headaches, upset stomachs, back pains and stuffy nose. You can continue to use Cialis, but talk to your doctor to ensure no health problems will be aggravated.

A variety of drugs could affect Cialis. For this reason, it is important to discuss with your doctor about certain medications, health history and other concerns about treating erectile dysfunction.