Archive for December, 2009

Health Tip: When Bedwetting Signals Another Problem

Thursday, December 31st, 2009

Bedwetting affects many young children and often doesn’t indicate a serious medical issue.

However, the Nemours Foundation says, if bedwetting starts all of a sudden or is accompanied by these other factors, it’s time to call a pediatrician.
Bedwetting that resumes after a child has had dry nights for at least six months.
Sudden behavioral problems, either at home or at school.
Complaints from your child that there’s burning or pain during urination.
An increase in the frequency of urination.
An increase in appetite or thirst.
Swelling of the ankles or feet.
Bedwetting that continues at age 7 or older.

Intense exercise may lower your blood count

Thursday, December 24th, 2009

Exercise is good for you, but watch it: A new study found that young men engaging in strenuous physical activity are “an often overlooked” group that’s at risk for low blood counts and iron deficiency.

Dr. Drorit Merkel from the Chaim Sheba Medical Center, Tel-Hashomer and colleagues studied 153 males, all 18 years old, who were training to join an elite combat unit in the Israel Defense Force.

In the September Journal of Adolescent Health, the investigators report that before the start of training, about 18 percent of the recruits had low blood count, or anemia. That rate almost tripled after six months of intensive military training, to just over 50 percent.

The rate of iron deficiency nearly doubled, from about 15 percent to 27 percent. The researchers do not report whether the recruits had any symptoms of anemia.

The researchers point out that the males in the study had a higher-than-average rate of anemia to begin with, which could explain some of the results. That’s because recruits who intend to compete for membership in elite units often participate in intense pre-recruitment preparatory training.

“Iron deficiency and anemia,” the investigators point out, “are generally uncommon findings in healthy male adolescents. However, athletes who engage in strenuous physical activity are known to be at increased risk for so-called ’sports anemia.’”

So why the higher risk? Potential reasons include drinking lots of water, which temporarily dilutes the blood and damage to blood cells that can result from high levels of physical activity.

“The prevalence of iron deficiency in new recruits indicates a military public health issue, and the preventive and therapeutic implications of these findings require further evaluation,” Merkel and colleagues conclude.

Lower Drinking Age Linked to Later-Life Problems

Thursday, December 17th, 2009

People who grew up in a place and time when they could legally buy alcohol before age 21 are more likely than others to be alcoholics or have a drug problem, even well into adulthood, new research shows.

“The effect lingers,” said study author Dr. Karen Norberg, a research instructor in psychiatry at Washington University in St. Louis. “A drinking-age law of 21 is associated with lower risks of long-term problems with alcohol use.”

The study is published online Sept. 18 in the journal Alcoholism: Clinical and Experimental Research.

Norberg and her research colleagues analyzed surveys of nearly 34,000 people born in the United States between 1948 and 1970, examining their records to determine if rates of alcoholism and drug abuse differed depending on their states’ liquor-buying laws at the time the participants were teens or young adults.

In the early 1970s, 26 states lowered the drinking age to 18 after the federal voting age was lowered to 18, Norberg said. After passage in 1984 of the National Minimum Drinking Age Act, the federal government pressured states to increase the drinking age or forfeit highway funds.

By the late 1980s, most states had complied, raising the drinking age back to 21. Louisiana, the researchers noted, was the last to do so, in 1995.

In the study, people who had been allowed to buy liquor legally before age 21 were 33 percent more likely to have suffered from alcoholism in the year before they were surveyed.

Drinking at a younger age also was found to increase the risk of abusing other drugs. Those allowed to drink legally before age 21 were 70 percent more likely to have had a problem with drugs than were those who had to wait until 21 to drink legally, the study found.

No differences were detected between men and women, various ethnicities or age groups.

The findings suggest, Norberg said, that the frequency or intensity of drinking in late adolescence has long-term effects.

A study released earlier this year reported that states that allow the suspension of a driver’s license for any underage alcohol violation and states with zero-tolerance laws that make it illegal for young people to drive with any level of alcohol in their system have fewer drunk-driving accidents.

So-called use-and-lose laws resulted in 5 percent fewer auto accidents related to drinking, the study found. It, too, was published in Alcoholism: Clinical and Experimental Research.

Norberg’s study is believed to be the first to look at the very long-term effects of lowered drinking ages.

The study “substantiates something that has not been substantiated this way before — that the [legal] drinking age really has long-term impact,” said Dr. Marc Galanter, director of the division of alcoholism and drug abuse at New York University School of Medicine. “Even in [people’s] 40s and 50s, this impact was felt.”

Though people nationwide continue to debate what the ideal legal drinking age should be, with some again calling for a lower age, Galanter said the results suggest that keeping the status quo would be good.

Traci Toomey, an associate professor of public health at the University of Minnesota, who also has researched the topic, agreed. The new study, she said, provides “another piece of the puzzle that looks at the policy from another angle.”

Norberg, however, said that though her research poses a “strong argument” for keeping the drinking age at 21, “there might be some other solution,” such as the drinking “learner’s permits” that some have proposed.

That concept aims to change the youth culture from acceptance of excessive drinking to preference for limited alcohol consumption. One way to do this, proponents say, could be to allow someone younger than 21 to apply for a learner’s permit that allows limited use of alcohol under monitored conditions.

Men with rare gender disorder can still have kids

Thursday, December 10th, 2009

Men with a rare disorder in which they carry extra female genes can still have children if they undergo a surgical procedure for collecting their sperm, according to a new study.

Men with Klinefelter’s syndrome carry an extra copy of the X chromosome; normally men have one each of the X and Y chromosomes, and women have two X chromosomes. Men with Klinefelter’s syndrome carry XXY, and the main effect of the disorder is less fertility.

However, Dr. Ranjith Ramasamy and colleagues at New York-Presbyterian Hospital in New York used a surgery technique to retrieve sperm from 45, or two-thirds, of their 68 patients. Of 91 total attempts, 62 were successful.

More than half - 57 percent - of the men’s partners became pregnant after the sperm was combined with their partners’ eggs in the laboratory, in a procedure known as in vitro fertilization. Not all of those pregnancies made it to term, however: Overall, 45 percent of those couples who attempted to conceive using in vitro fertilization had children.

The researchers report their results In the September Journal of Urology. Sperm retrieval was more likely to be successful in younger men, with success rates of 71 percent for men 22 to 30 years old, 86 percent for those 31 to 35, and 50 percent for those 36 to 52 years old, they report. The oldest patient to undergo successful retrieval was 45.

Sperm retrieval rates were lower among men given testosterone replacement therapy, which is not uncommon in men with Klinefelter’s syndrome.

Given that sperm can be retrieved from men with the syndrome up until at least age 35, the researchers conclude, men should not rush to have their sperm obtained during adolescence, the authors conclude.

Middle-Age Heart Risk Factors Shorten Men’s Lives

Thursday, December 3rd, 2009

Middle-aged men with risk factors for heart disease such as smoking, high blood pressure and high cholesterol are taking 10 to 15 years off their lives compared to men without these troubles, British researchers say.

Although death from heart disease has been declining, in part due to better control of cardiovascular risk factors and better care, this is the first study that looks at death from heart disease in terms of life expectancy, the researchers said.

“The good news is that all of us can make changes to live a healthy life,” said lead researcher Dr. Robert Clarke, a reader in epidemiology at University of Oxford. “Those changes, we now know, can translate into a 10- to 15-year difference in life expectancy.”

Although not the subject of this study, Clarke suspects the same lessons would apply to women.

The report is published in the Sept. 18 online edition of the British Medical Journal.

For the study, a team led by Clarke, a reader in epidemiology at the University of Oxford, collected data on nearly 19,000 men ranging from 49 to 69 years of age. The men all participated in what’s known as the Whitehall Study and were first evaluated between 1967-1970.

At the start of the study, the men completed a questionnaire that included questions about their medical history, smoking, employment and marital status. In addition, height, weight, blood pressure, lung function, cholesterol and blood sugar levels were also measured.

After about 28 years of follow-up, 7,044 surviving men were examined again in 1997.

When the study began, 42 percent of the men smoked, 39 percent had high blood pressure and 51 percent had high cholesterol. By 1997, about two-thirds had stopped smoking and their blood pressure and cholesterol levels had also dropped, the researchers noted.

Despite these changes in risk factors for heart disease, men who had three heart risk factors in middle age had a threefold higher risk of dying from heart disease and a twofold increased risk of dying from other causes, compared with men with none of these risk factors, Clarke’s team found.

In fact, men who had all three risk factors at the time they entered the study lived 10 years less than men with none of the risk factors. Life expectancy after 50 was an additional 23.7 years for men with three risk factors, compared with 33.3 years for men without the risk factors, the researchers found.

When Clarke’s group evaluated the men using a risk score that took into account smoking, diabetes, employment, blood pressure, cholesterol and body-mass index. Men in the highest (worst) five percent of this risk score cut their life expediency by 15 years from age 50, compared with men with the lowest risk score (20.2 vs. 35.4 years).

“Cardiovascular risk factors are well-documented to result in premature cardiovascular events and cardiovascular deaths,” said Dr. Gregg C. Fonarow, a professor of cardiology at the University of California, Los Angeles. “This study quantifies how the presence or absence of certain cardiovascular risk factors in middle age influences life span.”

Three modifiable risk factors — smoking, high blood pressure and high cholesterol — seemed most dangerous, Fonarow noted.

“Individuals who choose to not treat and control these major cardiovascular risk factors should recognize they may be giving up, on average, as much as 10 to 15 years of life by doing so,” he said. “More needs to be done to identify, treat and control major cardiovascular risk factors to reduce the global burden of cardiovascular events and premature cardiovascular deaths.”

While this study was conducted in England, the problem is equally prevalent in the United States.

For example, a recent study in the Sept. 14 online edition of Circulation found that after decades of steady progress against heart disease, the illness appears poised for a comeback. The study found that only 7.5 percent of Americans are now in the clear when it comes to heart disease risk factors.

The continuing U.S. obesity epidemic may bear much of the blame for the downturn, the researchers said.

“Our results raise the concern that a worsening cardiovascular risk profile in the population could potentially lead to increases in the incidence and prevalence of cardiovascular disease,” said lead researcher Dr. Earl S. Ford, from the U.S. Centers for Disease Control and Prevention. “Potential increases in cardiovascular disease and diabetes could affect the nation’s medical costs.”